Pyridine derivatives useful as cyclooxygenase inhibitor

Details Pyridine derivatives useful as cyclooxygenase inhibitor Pyridine derivatives useful as cyclooxygenase inhibitor

C - Chemistry, Metallurgy

07

D

C07D 213/85 (2006.01) A61K 31/4418 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) C07D 213/26 (2006.01) C07D 213/30 (2006.01) C07D 213/38 (2006.01) C07D 213/40 (2006.01) C07D 213/48 (2006.01) C07D 213/61 (2006.01) C07D 213/82 (2006.01) C07D 213/84 (2006.01)

Patent

CA 2433623

A compound of the formula (I), wherein R1 is hydrogen, halogen, carbymoyl, cyano, formuly, or lower alkyl optionally substituted with halogen, amino or a protected amino; R2 is hydrogen, halogen, cyano or lower alkoxy; R3 is phenyl or pyridyl, each of which is substituted with lower alkoxy; and R4 is lower alkoxy; provided that either R1 or R2 is hydrogen, then the other is other than hydrogen, or its salts, which are useful as a medicament.

L'invention concerne un composé correspondant à la formule (I) ou ses sels, lesquels sont utiles en tant que médicament. Dans ladite formule (I): R?1¿ représente hydrogène, halogène, carbamoyl, cyano, formyle ou alkyle inférieur éventuellement substitué par halogène, amino ou un groupe amino protégé; R?2¿ représente hydrogène, halogène, cyano ou alcoxy inférieur; R?3¿ représente phényle ou pyridyle, chacun de ces groupes étant substitué par un alcoxy inférieur; et R?4¿ représente alcoxy inférieur. Si l'un des symboles R?1¿ ou R?2¿ représente hydrogène, l'autre représente alors un groupe autre que l'hydrogène.

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