Pyridine derivatives useful as inhibitors of pkc-theta

Details Pyridine derivatives useful as inhibitors of pkc-theta Pyridine derivatives useful as inhibitors of pkc-theta

C - Chemistry, Metallurgy

07

D

C07D 213/74 (2006.01) A61K 31/44 (2006.01) A61K 31/4523 (2006.01) A61P 3/00 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) C07D 213/85 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2602250

Disclosed are novel compounds of formula (I) wherein R1, R2 and R3 are as defined herein, which are useful as inhibitors of PKC-theta and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC-theta, including immunological disorders and type II diabetes. This invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

La présente invention propose des composés innovants de formule (I) dans laquelle R?1#191, R?2#191 et R?3#191 sont tels que définis ici. Ces composés sont utilisables en tant qu'inhibiteurs de PKC-thêta et ils permettent donc de traiter divers troubles et maladies qui sont induits ou entretenus par l'activité de PKC-thêta, y compris des troubles immunologiques et le diabète de type II. La présente invention se rapporte également à des compositions pharmaceutiques comprenant ces composés, à des procédés d'utilisation de ces composés dans le traitement de divers troubles et maladies, aux procédés de préparation de ces composés et aux intermédiaires utiles dans ces procédés.

Affiliated with

Also associated with

Rating

Pyridine derivatives useful as inhibitors of pkc-theta does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pyridine derivatives useful as inhibitors of pkc-theta, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyridine derivatives useful as inhibitors of pkc-theta will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1664257