Pyridinecarboxylic esters, processes for their preparation...

Details Pyridinecarboxylic esters, processes for their preparation... Pyridinecarboxylic esters, processes for their preparation...

C - Chemistry, Metallurgy

07

D

260/242, 260/296

C07D 213/80 (2006.01) C07D 213/85 (2006.01) C07D 401/04 (2006.01) C07D 491/04 (2006.01) C07D 491/048 (2006.01)

Patent

CA 1208216

ABSTRACT OF THE DISCLOSURE Pyridinecarboxylic acid esters of the formula Image (I) in which R is an optionally substituted aryl or heterocyclic radical, R1 and R2 are hydrogen, alkyl, aryl, aralkyl, acyloxyalkyl or hydroxyalkyl, or R1 with X forms a carbonyl-containing heterocyclic ring, X is -CN, -CO-R4, -COOR5 or -SO2R6, R4, R5 and R6 are various optionally substituted radicals, and R3 is different from R5 and is a substituted- or interrupted-hydrocarbon radical, or pharmaceutically acceptable salts thereof control the otherwise negative effects of ischaemia and/or hypoxia.

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