Pyridinium compounds

Details Pyridinium compounds Pyridinium compounds

C - Chemistry, Metallurgy

07

D

167/211, 167/8,

C07D 213/38 (2006.01) A01N 43/40 (2006.01) C07D 401/10 (2006.01)

Patent

CA 1239644

- 29 - ABSTRACT PYRIDINIUM COMPOUNDS Pyridinium compounds containing a cation having the formula Ia or Ib Image (Ia) or Image (Ib) and a pharmaceutically acceptable cation are useful as pharmaceuticals, particularly as anti-fungal agents. In formulae Ia and Ib R1 is alkyl of at least 3 carbon atoms or aralkyl; R2 and R5 are hydrogen or various defined substituents; R3 and R4 are hydrogen or lower alkyl; R6 and R7 are lower alkyl or aryl(lower)alkyl or R6 and R7 represent a group having formula II -(CH2)2-A-(CH2)2- (II) (where A is -(CH2)n-, O, S or NR8 where n is 0, 1 or 2 and R8 is lower alkyl) or a mono- or di- (lower alkyl) substitution product of a group having formula II.

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