Pyridinone derivatives for treatment of atherosclerosis

Details Pyridinone derivatives for treatment of atherosclerosis Pyridinone derivatives for treatment of atherosclerosis

C - Chemistry, Metallurgy

07

D

C07D 215/36 (2006.01) A61K 31/47 (2006.01) A61P 9/10 (2006.01) C07D 211/74 (2006.01) C07D 213/68 (2006.01) C07D 215/22 (2006.01) C07D 221/04 (2006.01) C07D 401/12 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 495/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2425268

Compounds of formula (I): (see formula I) are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating atherosclerosis.

L'invention concerne des composés représentés par la formule (I) utilisés en thérapie comme inhibiteurs de l'enzyme L¿p?-PLA¿2?, notamment pour traiter l'athérosclérose.

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