Pyrido(2,1-b)quinazolin-ones and their methods of preparation

Details Pyrido(2,1-b)quinazolin-ones and their methods of preparation Pyrido(2,1-b)quinazolin-ones and their methods of preparation

C - Chemistry, Metallurgy

07

D

260/242.01

C07D 471/04 (2006.01) C07D 491/14 (2006.01) C07D 491/147 (2006.01)

Patent

CA 1197843

A B S T R A C T The present invention relates to the following generic series: Image where R1 is hydrogen; R2 is hydrogen, loweralkyl of 1 to 3 carbon atoms, halogen, hydroxy or loweralkoxy of 1 to 3 carbon atoms; R3 is hydrogen, loweralkyl of 1 to 3 carbon atoms, halogen, loweralkoxy of 1 to 3 carbon atoms, or carbo- loweralkyl of 1 to 3 carbon atoms; R2 and R3 together may be methylenedioxy; R4 is hydrogen; R5 is hydrogen or 7-lower- alkyl of 1 to 3 carbon atoms, or R5 may be 6-carboxy when R2 and R3 are methylenedioxy; and R6 is hydrogen, carboxy or carboxamido, with the proviso that R2, R3, R5 and R6 may not all be hydrogen at the same time, that R2 and R3 may both be hydrogen or both other than hydrogen. These compounds have utility as antiallergy agents.

263758

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