Pyrido[2,3-d]pyrimidines useful as hcv inhibitors, and...

Details Pyrido[2,3-d]pyrimidines useful as hcv inhibitors, and... Pyrido[2,3-d]pyrimidines useful as hcv inhibitors, and...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/519 (2006.01) A61P 31/14 (2006.01)

Patent

CA 2608301

The present invention relates to the use of pyrido[2,3-d]pyrimidines as inhibitors of 10 HCV replication as well as their use in pharmaceutical compositions aimed to treat or combat HCV infections. In addition, the present invention relates to pyrido- [2,3-d]pyrimidines co mpounds per se and their use as medicines. The present invention also concerns processes for the preparation of such compounds, pharmaceut ical compositions co mprising them, and combinations of said compounds 15 with other anti-HCV agents.

L'invention concerne l'utilisation de pyrido[2,3-d]pyrimidines en tant qu'inhibiteurs de réplication du virus de l'hépatite C ainsi que leur utilisation dans des compositions pharmaceutiques destinées à traiter ou à combattre des infections par le virus de l'hépatite C. L'invention concerne également des composés pyrido-[2,3-d]pyrimidines en soi et leurs utilisation en tant que médicaments. L'invention concerne en outre des procédés de préparation desdits composés, des compositions pharmaceutiques les comprenant, et des combinaisons desdits composés avec d'autres agents antivirus de l'hépatite C.

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