Pyrido [4,3-b] indoles and methods of use

Details Pyrido [4,3-b] indoles and methods of use Pyrido [4,3-b] indoles and methods of use

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2760541

New heterocyclic compounds that may be used to modulate a histamine receptor in an individual are described. Pyrido[4,3-b]indoles are described, as are pharmaceutical compositions comprising the compounds and methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder.

L'invention porte sur de nouveaux composés hétérocycliques qui peuvent être utilisés pour moduler un récepteur de l'histamine chez un individu. Des pyrido[4,3-B]indoles sont décrits, ainsi que des compositions pharmaceutiques comprenant les composés et des procédés d'utilisation des composés dans une variété d'applications thérapeutiques, comprenant le traitement d'un trouble cognitif, d'un trouble psychotique, d'un trouble à médiation par neurotransmetteur et/ou d'un trouble neuronal.

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