Pyrido [5, 4-d] pyrimidines as cell proliferation inhibitors

Details Pyrido [5, 4-d] pyrimidines as cell proliferation inhibitors Pyrido [5, 4-d] pyrimidines as cell proliferation inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2736306

The present invention encompasses compounds of general formula (1) wherein the groups R1 to R4, X1, X2, X3, L1 and L2 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or anomalous cell proliferation, and the use thereof in such a treatment.

La présente invention concerne des composés de formule générale (1) dans laquelle les groupes R1 àR4, X1, X2, X3, L1 et L2 sont définis comme décrit dans la revendication 1, qui sont adaptés pour le traitement de maladies caractérisées par une prolifération cellulaire anormale, et lutilisation de ceux-ci dans un tel traitement.

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