C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/551 (2006.01) A61K 31/553 (2006.01) A61P 7/12 (2006.01) A61P 13/00 (2006.01) C07D 221/00 (2006.01) C07D 243/00 (2006.01) C07D 267/00 (2006.01) C07D 498/04 (2006.01)
Patent
CA 2358895
The present invention provides benzoheterocyclic carboxyamides, particularly pyridobenzodiazepine and pyridobenzoxazepine carboxyamides, of general formula (I), wherein: W is O or NH, optionally substituted, as well as methods and pharmaceutical compositions utilizing these compounds for providing a temporary delay of urination or for the treatment of disorder which may be remedied or alleviated by vasopressin agonist activity, including diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, bleeding or coagulation disorders.
Cette invention a trait à des carboxyamides benzohétérocycliques notamment des pyridobenzodiazépine et pyridobenzoxazépine carboxyamides correspondant à la formule générale (I), formule dans laquelle W représente O ou NH, éventuellement substitué, ainsi qu'à des méthodes et à des compositions pharmaceutiques utilisant ces composés pour déclencher un retard temporaire de la miction ou pour traiter des troubles pouvant être soignés ou atténués par une activité d'agoniste de la vasopressine, notamment le diabète insipide, l'énurésie nocturne, la polyurie nocturne, l'incontinence urinaire, l'effusion sanguine et des troubles de la coagulation.
Failli Amedeo Arturo
Steffan Robert John
American Home Products Corporation
Ridout & Maybee Llp
Wyeth
LandOfFree
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