Pyridone derivatives as ap2 inhibitors

Details Pyridone derivatives as ap2 inhibitors Pyridone derivatives as ap2 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 213/64 (2006.01) A61K 31/4412 (2006.01) A61P 3/10 (2006.01) A61P 5/48 (2006.01) A61P 9/10 (2006.01) C07D 213/80 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01)

Patent

CA 2436854

aP2 inhibiting compounds are provided having the formula wherein A, Q, and X are as described herein. A method is also provided for treating diabetes and related diseases, especially Type II diabetes, employing such aP2 inhibitor or a combination of such aP2 inhibitor and another antidiabetic agent such as metformin, glyburide, troglitazone and/or insulin.

L'invention concerne des composés inhibant des aP2, présentant la formule dans laquelle A, Q, et X sont tels que définis dans la description. L'invention concerne également une méthode permettant de traiter des diabètes et des maladies associées, en particulier les diabètes de type II, à l'aide d'un tel inhibiteur de aP2 ainsi que d'un autre agent antidiabétique, tel que la metformine, la glyburide, la troglitazone et/ou l'insuline.

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