Pyridonecarboxylic acid derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 401/04 (2006.01) A61K 31/435 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2076982

- 72 ABSTRACT This invention relates to compounds represented by the following general formula or their pharmaceutically acceptable salts or esters, a process for preparation thereof and antitumor agents containing them as an effective ingredient III Image wherein R1 represents a straight- chain, branched or cyclic lower alkyl group or a phenyl group optionally substituted by fluorine atom(s), R2 and R3 each represent a hydrogen atom or a straight - chain, branched or cyclic lower alkyl group, R1 represents a hydrogen atom or -N (R5) R6 wherein R5 and R6 each represent a hydrogen atom or a straight-chain, branched or cyclic lower alkyl group, X represents a nitrogen atom or C - Y wherein Y represents a hydrogen atom, halogen atom, methyl group or methoxy group, m and n each represent an integer of 0 or 1, and ? represents a single bond or double bond.

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