Pyridopyrazinones derivatives insulin secretion stimulators,...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/4985 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2718402

The present invention relates to pyridopyrazinone derivatives of formula (I), wherein X, Y, Z1 W, A and R1 are as defined in claim 1, as insulin secretion stimulators. The invention also relates to the preparation and use of these pyridopyrazinone derivatives for the prophylaxis and/or treatment of diabetes and pathologies associated.

La présente invention concerne des dérivés de pyridopyrazinone de la formule (I), dans laquelle X, Y, Z1, W, A et R1 sont tels que définis dans la revendication 1, comme stimulateurs de la sécrétion dinsuline. Linvention concerne également la préparation et lutilisation de ces dérivés de pyridopyrazinone pour la prophylaxie et/ou le traitement du diabète et des pathologies associées.

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