Pyridopyrimidinone compounds, method for production thereof...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2503995

Compounds of formula (I), where: R¿1?, R¿2?, R¿3?, R¿4? are as defined in the description, the enantiomers, diastereomers, tautomers and addition salts thereof with a pharmaceutically-acceptable acid or base. Said compounds have kinase modulating properties and are useful in the treatment of cancer, diabetes, obesity etc.

Composés de la formule (I) dans laquelle : R1, R2, R3, R4, sont définis dans la description, leurs énantiomères, diastéréoisomères, tautomères, ainsi que leurs sels d'addition à un acide ou à une base pharmaceutiquement acceptable. Ces composés ont des propriétés modulatrices de kinases et sont utiles dans le traitement du cancer, du diabète, de l~obésité, etc.

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