A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/675 (2006.01) A61L 27/40 (2006.01) A61L 27/54 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2586421
The present invention provides method of treating and preventing vascular Inflammation, atherosclerosis, restenosis, plaque destabilization and bypass graft failure comprising the administration of a therapeutically effective amount, of pyridoxal-5'-phosphate or a pharmaceutically acceptable salt thereof. The present invention further provides an Intravascular stent for use with a narrowed artery having at least one surface reversibly bound with pyridoxal-5'-phosphate or a pharmaceutically acceptable salt thereof.
L'invention concerne un procédé qui permet de traiter et de prévenir l'inflammation vasculaire, l'athérosclérose, la resténose, la déstabilisation des plaques et l'échec d'une greffe de pontage en administrant une quantité thérapeutiquement efficace d'un pyridoxal-5'-phosphate ou d'un sel pharmaceutiquement acceptable de ce dernier. L'invention se rapporte également à un stent intravasculaire utilisé dans une artère rétrécie, dont une surface au moins est liée de manière réversible à un pyridoxal-5'-phosphate ou à un sel pharmaceutiquement acceptable de ce dernier.
Medicure International Inc.
Ridout & Maybee Llp
LandOfFree
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