Pyridoxine and pyridoxal analogues: cardiovascular therapeutics

C - Chemistry – Metallurgy – 07 – D

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C07D 213/40 (2006.01) A61K 31/44 (2006.01) A61K 31/4427 (2006.01) A61P 9/10 (2006.01) C07D 213/48 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2414188

The invention provides pyridoxal and pyridoxine analogues, pharmaceutical compositions containing pyridoxine and pyridoxal analogues, and methods of administering pharmaceutical compositions containing a therapeutically effective amount of at least one of these analogues. In accordance with the present invention, the pyridoxal and pyridoxine analogues can be used in the treatment of cardiovascular or related diseases and in the treatment of symptoms thereof.

Cette invention a trait à des analogues de pyridoxal et de pyridoxine, à des compositions pharmaceutiques contenant ces analogues ainsi qu'à des méthodes d'administration de ces compositions pharmaceutiques, consistant à administrer une quantité efficace du point de vue thérapeutique de l'un au moins de ces analogues. Il est possible d'utiliser ces analogues de pyridoxal et de pyridoxine pour traiter des maladies cardio-vasculaires ou connexes ainsi que pour en traiter les symptômes.

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