Pyridyl inhibitors of hedgehog signalling

Details Pyridyl inhibitors of hedgehog signalling Pyridyl inhibitors of hedgehog signalling

C - Chemistry, Metallurgy

07

D

C07D 213/40 (2006.01) C07D 213/38 (2006.01) C07D 213/56 (2006.01) C07D 213/70 (2006.01) C07D 213/75 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/04 (2006.01) C07D 417/12 (2006.01) C07F 9/142 (2006.01)

Patent

CA 2579002

The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I: wherein A, X, Y, R1, R2, R3, R4, and n are as described herein.

La présente invention a trait à de nouveaux inhibiteurs de la signalisation hedgehog qui sont utiles en tant qu'agents thérapeutiques pour le traitement de malignités, les composés étant de formule générale (I), dans laquelle: A, X, Y, R1, R2, R3, R4, et n sont tels que définis dans la description.

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