Pyridyl n-oxides

C - Chemistry – Metallurgy – 07 – D

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260/290.3, 260/2

C07D 213/89 (2006.01) C07D 405/12 (2006.01)

Patent

CA 1247092

ABSTRACT OF DISCLOSURE N-oxides of pyridyl carboxylic acid esters of the follow- ing formula are described: Image wherein R is Image wherein X is a hydrogen atom, straight or branched C1-C5-alkyl, C5-C12-cycloalkyl, 1-adamantyl, or cyclo- hexylacetyl, and wherein Y is a hydrogen atom, straight or branched C1-C5-alkyl, 2-ethylbenzofuranoyl-3, C5-C12-cycloalkyl, or 2-[(4-chlorophenoxy)-2-methylpropanoyloxy]ethyl; a process for the manufacture thereof, pharmaceutical compositions containing these compounds, and method of using the same. These compounds are suited for use in the treatment of hyperlipidemas.

453248

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