Pyridyl-piperazine derivative and a process for the...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/04 (2006.01) C07D 213/04 (2006.01) C07D 213/74 (2006.01)

Patent

CA 1098129

A B S T R A C T A novel 3-[4-(2'-pyridyl)-piperazin-1-yl]-1- -(3,4,5-trimethoxy-benzoyloxy-propane is prepared by reacting 3-[4-(2'-pyridyl)-piperazin-1-yl]-1-hydroxy- -propan with 3,4,5-trimethoxy-benzoic acid or with a reactive derivative thereof or by reacting 4-(2'- -pyridyl)-piperazine with a 1-(3,4,5-trimethoxy-benzoyl- oxy)-3-halogen-propane. The new compound and the pharmaceutically acceptable salts thereof have anti- arrhythmic activity.

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