Pyridyl substituted ketolide antibiotics

Details Pyridyl substituted ketolide antibiotics Pyridyl substituted ketolide antibiotics

C - Chemistry, Metallurgy

07

H

C07H 17/08 (2006.01) A61K 31/7048 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2523134

Antimicrobial macrolide and ketolide compounds are provided having formulas (XII), as well as pharmaceutically acceptable salts, esters or prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of the compounds.

La présente invention concerne des composés antimicrobiens macrolides et kétolides représentés par les formules (XII). L'invention concerne également certains de leurs sels, esters ou promédicaments pharmaceutiquement admis. L'invention concerne aussi des compositions pharmaceutiques comprenant de tels composés. L'invention concerne enfin des procédés permettant l'élaboration de ces composés.

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