Pyridyl sulfone derivatives as 5-ht receptor antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 213/74 (2006.01) A61K 31/44 (2006.01) A61K 31/496 (2006.01) A61K 31/53 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61K 31/551 (2006.01) A61K 31/5513 (2006.01) A61K 49/08 (2006.01) A61P 25/00 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2476350

The invention provides compounds of the formula (I) and methods of using those compounds for treating a disease or condition in a mammal wherein a 5-HT receptor, such as a 5-HT6 receptor, is implicated and modulation of a 5-HT function is desired, wherein A, G and W1-W3 are defined as herein.

L'invention concerne des composés de formule (I) ainsi que des procédés d'utilisation de ces composés dans le traitement d'une maladie ou d'un état pathologique chez un mammifère, dans lesquels un récepteur 5-HT, tel qu'un récepteur 5-HT¿6?, est impliqué et la modulation de la fonction de 5-HT souhaitée ; A, G et W¿1?-W¿3 ?étant tels que définis dans le descriptif.

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