C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/58 (2006.01) A61K 9/107 (2006.01) A61K 31/575 (2006.01) A61K 31/663 (2006.01) A61K 31/675 (2006.01) A61P 19/00 (2006.01) A61P 19/08 (2006.01) A61P 19/10 (2006.01) C07D 213/72 (2006.01)
Patent
CA 2192456
The present invention relates to certain optionally ring substituted pyridinylaminomethylidene bisphosphonic acid tetralkyl esters (I) and their use for the treatment of bone diseases, such as osteolytic bone diseases due to malignancy, Paget's disease and primary and secondary osteoporosis.
La présente invention concerne certains tétraalkyle esters de l'acide pyridinylaminométhylidène bisphosphonique, portant éventuellement des substitutions de cycle et ayant la formule (I), ainsi que leur utilisation dans le traitement de maladies des os telles que les maladies ostéolytiques dues à des tumeurs, la maladie osseuse de Paget et l'ostéoporose primaire ou secondaire.
Hannuniemi Ritva
Heikkila-Hoikka Marjaana
Kleimola Terttu
Lauren Leena
Liukko-Sipi Sirpa
Bayer Schering Pharma Aktiengesellschaft
Leiras Oy
Mccarthy Tetrault Llp
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