C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 491/04 (2006.01) C07D 491/10 (2006.01) C07D 491/113 (2006.01)
Patent
CA 2260213
The present invention provides a compound of formula (I) (see formula I) and its pharmaceutically acceptable salts, wherein R1, R2, R3, R4, R5 and m are as defined in claim 1. The present invention also provides processes for the preparation thereof, the use thereof in treating cytokines mediated diseases and/or cell adhesion molecules (CAMS) mediated diseases and pharmaceutical compositions for use in such therapy.
L'invention concerne un composé de formule (I) et ses sels pharmaceutiquement acceptables. Dans ladite formule (I), R<1>, R<2>, R<3>, R<4>, R<5> et m sont tels que définis dans la revendication 1. Elle se rapporte également à leurs procédés de préparation, leur utilisation dans le traitement de maladies à médiation cytokinique et/ou les maladies induites par des molécules d'adhésion cellulaires ainsi qu'à des compositions pharmaceutiques à utiliser dans une telle thérapie.
Kawai Akiyoshi
Kawai Makoto
Murata Yoshinori
Sakakibara Minoru
Takada Junji
Pfizer Inc.
Smart & Biggar
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