Pyridylpyrrole derivatives active as kinase inhibitors

A - Human Necessities – 61 – K

Patent

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A61K 31/444 (2006.01) A61K 45/06 (2006.01) A61P 9/10 (2006.01) A61P 11/00 (2006.01) A61P 13/08 (2006.01) A61P 13/12 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 25/28 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07D 471/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2535125

Pyridylpyrrole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.

L'invention concerne des dérivés de pyridylpyrrole de formule (I) et sels pharmaceutiquement acceptables de ces derniers, tels que définis dans la spécification, ainsi que des compositions pharmaceutiques comprenant ces derniers. Les composés de la présente invention peuvent être utiles en thérapie, dans le traitement de maladies associées à une activité protéine kinase déréglée, telles que le cancer.

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