Pyrimidine-4-one derivatives as ldl-pla2 inhibitors

Details Pyrimidine-4-one derivatives as ldl-pla2 inhibitors Pyrimidine-4-one derivatives as ldl-pla2 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 239/56 (2006.01) A61K 31/513 (2006.01) A61P 9/10 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2400554

Pyrimidone compounds of formula (I) are inhibitors of the enzyme Lp-PLA2 and are of use in treating atheroscelerosis.

L'invention concerne des composés de pyrimidone selon la formule (I). Ces composés sont des inhibiteurs de l'enzyme Lp-PLA2 et permettent de traiter l'athérosclérose.

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