Pyrimidine biosynthesis inhibitors useful as...

A - Human Necessities – 61 – K

Patent

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A61K 31/66 (2006.01) A61K 31/12 (2006.01) A61K 31/415 (2006.01)

Patent

CA 2069313

2069313 9106863 PCTABS00005 The pyrimidine biosynthesis inhibitors dichloroallyl lawsone, N-(phosphonoacetyl)-L-aspartic acid (PALA), pyrazofurin, and derivatives thereof, are useful as immunomodulatory and anti-inflammatory agents. Pharmaceutical formulations containing these compounds are useful for the treatment of autoimmune diseases, chronic inflammatory diseases, and of organ transplantation rejections.

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