Pyrimidine carboxylates and related compounds and methods...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 239/28 (2006.01) A61K 31/495 (2006.01) C07D 239/42 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/00 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07D 473/00 (2006.01)

Patent

CA 2230896

Compounds having utility as anti-inflammatory agents in general and, more specifically, for the prevention and/or treatment of immuno-inflammatory and autoimmune diseases are disclosed. The compounds are pyrimidine-containing compounds and, in one embodiment, are esters of the same. Methods are also disclosed for preventing and/or treating inflammatory conditions by administering to an animal in need thereof an effective amount of a compound of this invention, preferably in the form of a pharmaceutical composition.

Composés s'avérant utiles comme agents anti-inflammatoires d'une manière générale et, plus spécifiquement, pour la prévention et/ou le traitement des maladies immuno-inflammatoires et auto-immunes. Ces composés sont des composés contenant de la pyrimidine et, dans un mode de réalisation, sont des esters de celle-ci. L'invention porte également sur des méthodes de prévention et/ou de traitement des états inflammatoires par administration à un animal en ayant besoin d'une dose efficace d'un composé de cette invention, de préférence sous forme d'une composition pharmaceutique.

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