Pyrimidine compounds

Details Pyrimidine compounds Pyrimidine compounds

C - Chemistry, Metallurgy

07

D

C07D 239/48 (2006.01) A61K 31/505 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2476281

Pyrimidine derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.

L'invention concerne des dérivés de la pyrimidine, qui sont utiles en tant qu'inhibiteurs de TIE-2 et/ou de VEGFR-2. La présente invention se rapporte également à des procédés de fabrication de tels dérivés de la pyrimidine, ainsi qu'à des procédés d'utilisation de ceux-ci dans le traitement de maladies hyperprolifératives.

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