C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/04 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2502190
The present invention relates to substituted pyrimidines of formula (I), their preparation, pharmaceutical compositions containing them and their use as inhibitors of cyclin-dependent kinases (CDKs) and hence their use in the treatment of proliferative disorders and/or viral disorders.
La présente invention concerne des pyrimidines substituées de formule (I), leur préparation, des compositions pharmaceutiques les renfermant, et leur utilisation en tant qu'inhibiteurs des kinases dépendantes des cyclines et donc dans le traitement de troubles prolifératifs et/ou de troubles viraux.
Fischer Peter
Mcinnes Campbell
Meades Christopher
O'boyle Janice
Wang Shudong
Cyclacel Limited
Gowling Lafleur Henderson Llp
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