Pyrimidine compounds and methods for making and using the same

Details Pyrimidine compounds and methods for making and using the same Pyrimidine compounds and methods for making and using the same

C - Chemistry, Metallurgy

07

D

C07D 239/42 (2006.01) A01N 43/54 (2006.01) A61K 31/505 (2006.01) A61K 31/513 (2006.01) A61P 31/04 (2006.01) A61P 35/00 (2006.01) C07D 239/02 (2006.01) C07D 239/34 (2006.01) C07D 239/56 (2006.01)

Patent

CA 2435958

This invention discloses compounds, and pharmaceutically acceptable salts, solvates and prodrugs thereof, useful in therapeutically and/or prophylactically treating patients with an illness. Such illnesses include cancer, and secondary infections caused byPneumocystis carinii, Toxoplasma gondii, Mycobacterium tuberculosis, and Mycobacterium avium. The compounds themselves, methods of making these compounds, and methods of using these compounds are all disclosed. The compounds include 5-thiapyrimidines.

La présente invention concerne des composés et des sels, des solvates de ceux-ci répondant aux normes pharmaceutiques et des promédicaments, qui conviennent pour le traitement thérapeutique et/ou prophylactique de patients malades. Ces maladies comprennent le cancer et les infections secondaires causées par <i>pneumocystis carinii</i>, <i>toxoplasma gondii</i>, <i>mycobacterium tuberculosis</i> et <i>mycobacterium avium</i>. Cette invention concerne les composés eux-mêmes, des techniques de préparation de ces composés et des techniques d'utilisation de ces composés. Ces composés comprennent 5-thiapyrimidine. Fig. 2 1 solution aqueuse de peroxyde de sodium le reste ne se traduit pas

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