Pyrimidine compounds as anti-ictogenic and/or...

A - Human Necessities – 61 – K

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A61K 31/513 (2006.01) A61K 31/415 (2006.01) A61K 31/506 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61K 31/522 (2006.01) A61P 25/08 (2006.01)

Patent

CA 2444148

Methods and compounds useful for the inhibition of convulsive disorders, including epilepsy, are disclosed. The methods and compounds of the invention inhibit or prevent ictogenesis and/or epileptogenesis. Methods for preparing the compounds of the invention are also described. Compounds of the invention include formula (XIV), where R9-R12 are as in claim 1.

L'invention concerne des procédés et des composés servant à inhiber des troubles convulsifs, y compris l'épilepsie. Les procédés et les composés selon l'invention inhibent ou préviennent l'ictogénèse et/ou l'épileptogénèse. La présente invention porte également sur des procédés de préparation desdits composés. Dans un mode préféré de réalisation, les composés comprennent la formule :

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