Pyrimidine derivative having cell protecting effect and uses...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 239/50 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61P 9/10 (2006.01) A61P 25/00 (2006.01) C07D 239/46 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 403/04 (2006.01) C07D 417/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2720049

[Problem] To provide a prophylactic/therapeutic agent against, for example, nerve diseases and the like such as ischemic brain disease and neurodegenerative disease, or a prophylactic/therapeutic agent against diseases against which antioxidant action is effective, as a cell protecting agent, in particular as an inhibitor of brain cell damage or brain cell death. [Means of Solving the Problem] A compound represented by Formula (1), or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof: [Chemical 253] (see formula 1)

L'invention concerne un agent prophylactique ou thérapeutique pour les maladies nerveuses telles que les maladies cérébrales ischémiques et les maladies neurodégénératives ou analogues, ou un agent prophylactique ou thérapeutique pour les maladies pour lesquelles une activité antioxydante est efficace, qui peut agir en tant qu'agent de protection cellulaire, notamment un inhibiteur des blessures cellulaires cérébrales ou de la mort cellulaire cérébrale. L'invention concerne spécifiquement un composé représenté par la formule (1) ou un de ses sels, solvates, hydrates ou promédicaments pharmaceutiquement acceptables.

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