Pyrimidine derivatives

Details Pyrimidine derivatives Pyrimidine derivatives

C - Chemistry, Metallurgy

07

H

167/202, 260/258

C07H 19/073 (2006.01) A61K 31/70 (2006.01)

Patent

CA 1292987

Abstract Compounds of the formula Image I wherein R1 is halogen, C1-4-alkyl or halo-(C1-4- -alkyl), R2 is hydrogen, hydroxy or acyloxy, R3 and R4 each are hydrogen or C1-4-alkyl, R5 is aryl or aryloxy, X is 0 or NH and Y is -CO-CH2-, -CH(OH)-CH2, -CH2-CH2-, -S-, -SO- or -SO2- and tautomers thereof, possess antiviral activity and can be used in the form of medicaments for the control and preven- tion of viral infections. They can be manufactured according to methods known per se.

543984

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