Pyrimidine derivatives

Details Pyrimidine derivatives Pyrimidine derivatives

C - Chemistry, Metallurgy

07

D

167/222, 260/259

C07D 401/04 (2006.01) A61K 31/505 (2006.01) C07D 211/70 (2006.01) C07D 211/74 (2006.01) C07D 211/78 (2006.01) C07D 451/02 (2006.01) C07D 451/06 (2006.01)

Patent

CA 1244028

Abstract The novel pyrimidine derivatives of formula I Image I wherein R1, R2 and A have the significance given in the description, are dihydrofolate reductase inhibitors and can be used as antibacterial agents, optionally in com- bination with sulphonamides.

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