Pyrimidine derivatives

C - Chemistry – Metallurgy – 07 – D

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167/202, 260/258

C07D 405/04 (2006.01) A61K 31/70 (2006.01) C07H 19/06 (2006.01) C07H 19/073 (2006.01)

Patent

CA 1291125

Abstract Compounds of the formula Image wherein A is C1-8-alkylene, R1 is halogen, C1-4- -alkyl or halo-(C1-4-alkyl), R2 is hydrogen, hydroxy or acyloxy, R3 is hydrogen or C1-4-alkyl, R4 is aryl or aryloxy and X is O or NH, and tautomers thereof, possess antiviral activity and can be used in the form of medicaments for the control and preven- tion of viral infections. They can be manufactured according to generally known methods.

543986

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