Pyrimidine derivatives

Details Pyrimidine derivatives Pyrimidine derivatives

C - Chemistry, Metallurgy

07

D

C07D 239/28 (2006.01) A01N 51/00 (2006.01) C07C 311/48 (2006.01) C07C 323/67 (2006.01) C07D 213/79 (2006.01) C07D 213/81 (2006.01) C07D 239/52 (2006.01) C07D 239/56 (2006.01) C07D 239/60 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2047770

ABSTRACT OF THE DISCLOSURE A pyrimidine derivative having the formula, Image (1) wherein each of R1 and R2, which may be the same or different, is C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkoxy or halogen; R3 is hydrogen or C1-C6 alkyl; R4 is C1-C6 alkyl, halo C1-C6 alkyl, benzyl, phenyl or phenyl substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl, nitro and halogen; X is oxygen or sulfur; Z is nitrogen or CY4; each of Y1, Y2 and Y3, which may be the same or different, is hydrogen, halogen, C1-C6 alkyl or C1-C6 alkoxy; and Y4 is hydrogen, hydroxyl, mercapto, nitro, halogen, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C1-C6 alkoxy, C3-C6 alkenyloxy, C3-C6 alkynyloxy, halo C1-C6 alkyl, halo C2-C6 alkenyl, halo C2-C6 alkynyl, halo C1-C6 alkoxy, halo C3-C6 alkenyloxy, halo C3-C6 alkynyloxy, C1-C6 alkoxy C1-C6 alkyl, C3-C6 alkenyloxy C1-C6 alkyl, C3-C6 alkynyloxy C1-C6 alkyl, cyano, formyl, carboxyl, C1-C6 alkoxycarbonyl, C3-C6 alkenyloxycarbonyl, C3-C6 alkynyloxycarbonyl, phenyl, phenyl substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl and halogen, phenoxy, phenoxy substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl and halogen, phenylthio, phenylthio substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl and halogen, benzyloxy, benzyloxy substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxy- carbonyl and halogen, benzylthio, benzylthio substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl and halogen, Image , wherein each of R5 and R6, which may be the same or different, is hydrogen, C1-C6 alkyl, C3-C6 alkenyl or C3-C6 alkynyl, Image , wherein R5 and R6 are as defined above, Image , wherein R7 is C1-C6 alkyl, C3-C6 alkenyl or C3-C6 alkynyl and m is an integer of 0, 1 or 2, Image , wherein X1 is oxygen or sulfur, and R7 is as defined above, or Image , wherein R7 and m are as defined above, and n is an integer from 1 to 4.

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