Pyrimidine derivatives and drugs

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 403/02 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 239/32 (2006.01) C07D 239/34 (2006.01) C07D 239/42 (2006.01) C07D 401/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 453/02 (2006.01)

Patent

CA 2090027

2090027 9204333 PCTABS00011 The invention aims at obtaining a novel compound which is excellent in central nervous system selectivity and reduced in side effects and has an activity of improving the function of learning and memory, thus providing an excellent medicine for dementia. The invention relates to a compound represented by general formula (I), a pharmacologically acceptable salt thereof, and an agent for remedying the disturbance of learning and memory containing the same as the active ingredient of formula (I), wherein R1 and R2 may be the same or different from each other and each represents hydrogen, hydroxy, alkoxy, trifluoromethyl or halogen; A represents methyl, trifluoromethyl or tertbutyl; and Y represents O or NH.

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