Pyrimidine derivatives as posh and posh-ap inhibitors

Details Pyrimidine derivatives as posh and posh-ap inhibitors Pyrimidine derivatives as posh and posh-ap inhibitors

C - Chemistry, Metallurgy

07

D

C07D 409/14 (2006.01) A61K 31/506 (2006.01) A61P 25/28 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2668859

Pyrimidine derivatives are ubiquitination inhibitors that inhibit the ubiquitin ligase activity, particularly of POSH polypeptides, are useful for the treatment of viral infections and neurological disorders.

Les dérivés de pyrimidine sont des inhibiteurs d'ubiquitination qui inhibent l'activité de l'ubiquitine ligase, en particulier des polypeptides POSH, et sont utiles pour le traitement d'infections et de troubles neurologiques.

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