Pyrimidine derivatives for the treatment op gaba b mediated...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 239/42 (2006.01) A61K 31/495 (2006.01) A61P 25/00 (2006.01) C07D 239/48 (2006.01) C07D 403/12 (2006.01) C07D 405/04 (2006.01) C07D 413/04 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07F 7/02 (2006.01) C07F 9/02 (2006.01)

Patent

CA 2610742

The invention relates to novel heterocyclic compounds of the formula (I) in free base form or in acid addition salt form, in which R1, R2, R3, R4 and A are as defined in the specification, to their preparation, to their use as medicaments for the treatment of certain nervous system disorders and to medicaments comprising them.

L'invention concerne de nouveaux composés hétérocycliques de formule (I) sous forme de base libre ou sous forme de sel d'addition acide, formule dans laquelle R1, R2, R3, R4 et A sont tels que définis dans la description. De plus, l'invention concerne la préparation de ces composés, l'utilisation de ces composés comme médicaments dans le traitement de certains troubles du système nerveux, ainsi que des médicaments contenant ces composés.

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