C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/00 (2006.01)
Patent
CA 2542031
Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G', and G" represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
L'invention concerne des dérivés de pyrimidine de formule (I), dans laquelle J et Y représentent des anneaux aromatiques ou hétéroaromatiques, R?2¿, G, G' et G" représentent des groupes substituants et R?2a ¿représente l'hydrogène ou halogène, L représente un groupe de liaison, et M représente CH ou N. Cette invention a aussi pour objet des compositions pharmaceutiques renfermant ces composés et des méthodes d'utilisation desdits composés dans le traitement de maladies hyperprolifératives, telles que le cancer.
Bear Brian
Bierer Donald
Brands Michael
Bullion Ann-Marie
Chen Jianqing
Bayer Healthcare Llc
Bayer Pharmaceuticals Corporation
Borden Ladner Gervais Llp
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