Pyrimidine hydrazide compounds as pgds inhibitors

Details Pyrimidine hydrazide compounds as pgds inhibitors Pyrimidine hydrazide compounds as pgds inhibitors

C - Chemistry, Metallurgy

07

D

C07D 239/28 (2006.01) A61K 31/506 (2006.01) A61P 29/00 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 413/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2682629

This invention is directed to a compound wherein R1, R2, R3, R4 and L1 are as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma and/or chronic obstructive pulmonary disease (COPD).

Cette invention concerne un composé dans lequel R1, R2, R3, R4 et L1 sont tels que définis ici, une composition pharmaceutique comportant les composés et l'utilisation du composé pour traiter des troubles allergiques et/ou inflammatoires, en particulier des troubles tels que la rhinite allergique, l'asthme et/ou une maladie pulmonaire obstructive chronique (COPV).

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