Pyrimidine inhibitors of phosphodiesterase (pde) 7

Details Pyrimidine inhibitors of phosphodiesterase (pde) 7 Pyrimidine inhibitors of phosphodiesterase (pde) 7

C - Chemistry, Metallurgy

07

D

C07D 417/14 (2006.01) A61K 31/00 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61K 31/513 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61K 31/522 (2006.01) A61K 31/5375 (2006.01) A61K 31/55 (2006.01) A61P 37/00 (2006.01) A61P 37/06 (2006.01) C07D 239/42 (2006.01) C07D 403/04 (2006.01) C07D 403/12 (2006.01) C07D 417/12 (2006.01) C07D 491/10 (2006.01) C07D 498/10 (2006.01)

Patent

CA 2450934

Pyrimidine phosphodiesterase 7 (PDE 7) inhibitors of the following formula [insert chemical structure here] wherein R1, R2, Z, J and L are described herein, and analogs thereof are provided which are useful in treating T-cell mediated diseases.

La présente invention concerne des inhibiteurs pyrimidine de la phosphodiestérase 7 (PDE 7) représentés par la formule (I) dans laquelle R¿1?, R¿2?, Z, J et L sont tels que décrits dans le descriptif, et des analogues de ces derniers qui sont utiles dans le traitement des maladies induites par les cellules T. Formule (I)

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