Pyrimidine nucleoside derivatives

Details Pyrimidine nucleoside derivatives Pyrimidine nucleoside derivatives

C - Chemistry, Metallurgy

07

H

C07H 19/09 (2006.01) A61K 31/70 (2006.01) C07H 19/06 (2006.01)

Patent

CA 2226096

Compounds of formula (I), wherein R1 represents aryl, R2 represents lower alkyl, R3 represents an acyl group derived from an amino acid and R4 represents hydrogen or fluorine and the asterisk denotes that the configuration at the carbon atom indicated thereby is (S) or (R), and pharmaceutically acceptable acid addition salts thereof are antiviral agents.

Composés de formule (I) dans laquelle R?1¿ représente aryle, R?2¿ représente alkyle inférieur, R?3¿ représente un groupe acyle dérivé d'un acide aminé et R?4¿ représente hydrogène ou fluor, l'astérisque signifiant que la configuration de l'atome de carbone ainsi indiqué est (S) ou (R), et sels d'addition d'acide pharmaceutiquement acceptables desdits composés, utiles en tant qu'agents antiviraux.

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