Pyrimidine nucleoside derivatives having anti-tumor...

C - Chemistry – Metallurgy – 07 – H

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C07H 19/09 (2006.01) A61K 31/70 (2006.01) C07H 19/06 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2079413

Compounds of formula (I): (See Formula I) wherein: R1, R2 and R3 are independently selected from the group consisting of hydrogen atoms, optionally substituted alkanoyl groups and alkenylcarbonyl groups, PROVIDED THAT at least one of R1, R2 and R3 represents an unsubstituted alkanoyl group having from 5 to 24 carbon atoms, said substituted alkanoyl group or said alkenylcarbonyl group; and one of R4 and R5 represents a hydrogen atom and the other represents a cyano group; have valuable anti-tumor activity.

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