Pyrimidine nucleotide precursors for treatment of systemic...

A - Human Necessities – 61 – K

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A61K 31/7072 (2006.01) A61P 29/00 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2193967

Pyrimidine nucleotide precursors including acyl derivatives of cytidine, uridine, and orotate, and uridine phosphorylase inhibitors, md their use in enhancing resistance to sepsis or systemic inflammation are disclosed.

Cette invention se rapporte à des précurseurs de nucléotides de pyrimidine, qui contiennent des dérivés acyle de cytidine, d'uridine et d'orotate, ainsi que des inhibiteurs d'uridine-phosphorylase, et à l'utilisation de ces composés pour améliorer la résistance à la septicémie ou aux inflammations systémiques.

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