Pyrimidine substituted macrocyclic hcv inhibitors

Details Pyrimidine substituted macrocyclic hcv inhibitors Pyrimidine substituted macrocyclic hcv inhibitors

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) C07K 5/06 (2006.01)

Patent

CA 2677697

Compounds of the Formula (I) including a stereoisomer thereof, or an N-oxide, a pharmaceutically acceptable addition salt, or a pharmaceutically acceptable addition solvate thereof; useful as HCV inhibitors; processes for preparing these compounds as well as pharmaceutical compositions comprising these compounds as active ingredient.

L'invention concerne des composés de formule (I) comprenant un stéréoisomère ou un N-oxyde, ou un sel d'addition pharmaceutiquement acceptable ou un solvate d'addition pharmaceutiquement acceptable. Ces composés sont utiles comme inhibiteurs du virus de l'hépatite C (VHC). L'invention concerne également des procédés de préparation de ces composés, ainsi que des compositions pharmaceutiques les comprenant et agissant comme ingrédient actif.

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