C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/497 (2006.01) A61K 31/506 (2006.01) A61K 31/53 (2006.01) A61P 25/00 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01)
Patent
CA 2448602
The present invention relates to pyrimidine, triazine and pyrazine derivatives of the general formula (I), wherein R1, R2, R3, R4, X, Y and Z have the significances given in the specification ,as well as their pharmaceutically acceptable salts. The invention further relates to medicaments containing these compounds, their preparation and to their use for the control or prevention of acute and/or chronic neurological disorders.
L'invention porte sur des dérivés de pyrimidine, triazine et pyrazine de formule générale (I) dans laquelle: R?1¿, R?2¿, R?3¿, R?4¿, X, Y et Z ont les significations données dans la description, sur leurs sels pharmacocompatibles, sur des médicaments contenant ces composés et leur préparation et leurs utilisations pour contrôler ou prévenir les troubles neurologiques aigus et/ou chroniques.
Binggeli Alfred
Maerki Hans-Peter
Masquelin Thierry
Mutel Vincent
Wilhelm Maurice
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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