Pyrimidinone compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 239/56 (2006.01) A61K 31/506 (2006.01) A61P 9/10 (2006.01) C07D 401/14 (2006.01) C07D 403/06 (2006.01)

Patent

CA 2371671

Pyrimidinone compounds of formula (I) are inhibitors of the enzyme Lp-PLA2 and of use in therapy, in particular for treating atherosclerosis.

Ces composés pyrimidinones correspondant à la formule (I) constituent des inhibiteurs de l'enzyme Lp-PLA¿2? et sont utiles en thérapie, notamment pour traiter l'athérosclérose.

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