Pyrimidinone derivatives and their use in the treatment of...

Details Pyrimidinone derivatives and their use in the treatment of... Pyrimidinone derivatives and their use in the treatment of...

C - Chemistry, Metallurgy

07

D

C07D 239/91 (2006.01) A61K 31/505 (2006.01) A61P 9/10 (2006.01) C07D 239/36 (2006.01) C07D 239/70 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/14 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2459746

Compounds of formula (I) are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating athereosclerosis.

L'invention concerne des composés de la formule (I), en tant qu'inhibiteurs de l'enzyme Lp-PLA¿2? pouvant être utilisés à des fins thérapeutiques, en particulier pour le traitement de l'athérosclérose.

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