Pyrimidinones as casein kinase ii (ck2) modulators

Details Pyrimidinones as casein kinase ii (ck2) modulators Pyrimidinones as casein kinase ii (ck2) modulators

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) A61K 31/513 (2006.01) A61P 35/00 (2006.01) C07D 405/04 (2006.01)

Patent

CA 2683209

A compound having Formula I :or a pharmaceutically acceptable salt thereof, wherein X, R, R and R are as defined in the specification; pharmaceutical compositions thereof; and methods of use thereof. The compounds of Fomula I are inhibitors of Casein kinase II (CK2) pathways.

L'invention concerne un composé ayant la formule I : ou un sel pharmaceutiquement acceptable de celui-ci, dans laquelle X, R, R et R sont tels que définis dans la description ; les compositions pharmaceutiques de celui-ci et des procédés d'utilisation de celui-ci. Les composés de la formule I sont des inhibiteurs des voies de la caséine kinase II (CK2).

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